Police said the 23-year-old man was woken about 2am on June 12 when five unknown men entered his residence in Ocean Avenue.

One of the five men allegedly assaulted the 23 year old while the others allegedly began stealing items from the residence.

"Police believe that a number of items including drugs, cash and a television were stolen from the premises during the offence," a statement from NSW Police said.

The men then fled the scene in what police believe to have been a vehicle.

The 23-year-old man was taken to Tomaree Community Hospital for treatment to lacerations to his head, during which time police were called.

Port Stephens-Hunter Police District officers attended the hospital and spoke with the man.

Police then went to the Ocean Avenue residence and established a crime scene.

During a search of the residence police allegedly found cannabis, MDMA, ketamine, amphetamine, LSD, magic mushrooms and other substances believed to be illicit drugs.

The man was arrested upon his release from hospital and was taken to Nelson Bay Police Station.

He was charged with 11 counts of possess prohibited drug, three counts of supply prohibited drug and goods in custody.

He was refused bail and was due to appear at Raymond Terrace Local Court on Thursday, June 13.

Detectives from Port Stephens-Hunter Police District are continuing to investigate the home invasion incident.

Anyone with information is urged to contact Raymond Terrace Police Station on (02) 4983 7599 or Crime Stoppers on 1800 333 000.