It was a "devastating blow" to hear this week that three Sydney music venues would close, said state Labor spokesman for music John Graham, who also said there were additional venues on the brink.

Venue 505, The Lansdowne Hotel and Giant Dwarf announced this week they would close their live music operations.

"Our worry is we will lose these bits of the social infrastructure of the city when we get through to a better day," Mr Graham said.

"We will lose more venues, that's the sad truth at the moment."

Many live music venues have been under pressure for years, which operators have attributed in part to various government restrictions including the city's now defunct lock-out laws, designed to curb alcohol-fuelled violence.

Labor is supportive of Chief Health Officer Kerry Chant's health recommendations, but the state opposition believes live music venues which shut due to COVID-19 pandemic restrictions now need support.

Premier Dominic Perrottet said on Friday that the government would do "whatever it takes" to revitalise Sydney and Parramatta's city centres.

"I feel for many of those businesses and businesses right across our state have done it tough during this pandemic," Perrottet said.

"I am completely confident the Sydney CBD will be thriving again, as it was post-Delta last year."

Australian Associated Press