The Australian Federal Police have charged nine people across NSW, Queensland and the Northern Territory, dismantling the Colombian operation they say was capable of putting hundreds of kilograms of cocaine on the streets.

Police arrested a Western Sydney man at a service station at Heatherbrae on Thursday night as he was travelling from Queensland to Sydney allegedly couriering 11kg of cocaine inside two fridges in the back of a ute.

AFP Assistant Commissioner Kirsty Schofield said it came as Operation Merriden uncovered an "industrial-sized, purpose-built cocaine production laboratory" at Durong, about 300km northwest of Brisbane.

Police allege cocaine hidden in another substance inside buckets was being extracted at the rural property, which is believed to have been capable of producing 700kg of the drug.

Six people were charged in Queensland and a 33-year-old man, believed to be receiving instructions from overseas, was arrested in Darwin.

The AFP had been watching the set-up of the facility in rural Queensland and the 11kg of cocaine seized at Heatherbrae was the first batch the lab had produced.

Some of those arrested on Thursday have links to outlaw motorcycle gangs.

"We believe this syndicate was planning to distribute hundreds of kilograms of cocaine from this custom-built laboratory," Assistant Commissioner Schofield said on Friday.

"What we found was that this syndicate was an unrelenting, well-resourced cartel that has gone to significant lengths to conceal themselves from Australian law enforcement.

"We believe the Australian arm of this syndicate was on-selling these drugs to other distributors.

"These organised crime syndicates are well-resourced and are operating as international business enterprises using multi-pronged approaches to achieve their business outcomes."